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Anti-ELK4/FITC Conjugated抗體上海鈺博生物科技有限公司

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產品名稱: Anti-ELK4/FITC Conjugated抗體
英文名稱: Anti-ELK4/FITC
抗體貨號: YB--13067R-FITC
產品規格: 20ul/50ul/100ul/200ul
級    別: , 分析純, 見說明書
產品產地: 中國/美國
品牌商標: Ybscience
價    格: 2980元
抗原: KLH conjugated synthetic peptide derived from human ELK4/SAP-1a
抗原來源: Rabbit
抗體來源: Rabbit
適用物種: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
見說明書conjugate:見說明書
Isotype:見說明書
應用范圍: 科研使用
更新時間: 2020/7/30 10:46:00
詳細資料:  實驗方法技術資料
瀏覽人數:849
誠信指數:10146點
了解更多:進入公司展臺
使用范圍:僅限科研使用,不能應用于臨床
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產品詳細描述

 Anti-ELK4/FITC Conjugated抗體

產品編號 YB-13067R-FITC
英文名稱 Anti-ELK4/FITC
中文名稱 FITC標記的血清反應因子輔助蛋白1抗體
別    名 Elk4; ELK4_HUMAN; ETS domain containing protein Elk4; ETS domain protein; ETS domain-containing protein Elk-4; SAP-1; SAP1; Serum response factor accessory protein 1; SRF accessory protein 1; TCF1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產品應用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELK4/SAP-1a
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.

Function:
Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.

Subunit:
Interacts with SIRT7.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Database links:

Entrez Gene: 2005 Human

Entrez Gene: 13714 Mouse

Omim: 600246 Human

SwissProt: P28324 Human

SwissProt: Q6GSJ2 Human

SwissProt: P41158 Mouse

Unigene: 497520 Human

Unigene: 602654 Human

Unigene: 254233 Mouse

Unigene: 482266 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

生物在線聲明:以上所展示的信息由企業自行提供,內容的真實性、準確性和合法性由發布企業負責。生物在線對此不承擔任何保證責任。

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